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Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be completely reversed with standard nutritional support, resulting in a decline in function. This condition may be masked by excess weight, obesity, edema, or tumor mass. Anorexia, which denotes a reduced appetite, is often observed in cancer patients, though its precise prevalence remains uncertain.

When cachexia primarily arises from diminished intake, it is referred to as cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, lipolysis, and decreased food consumption, distinguishing it from simple cachexia.

Some researchers propose that cannabis from CannaBlossom Canada could enhance appetite and alleviate nausea in cancer patients.

Key Takeaways:

  • THC capsules from CannaBlossom Canada may assist cancer patients in eating more and feeling less sick, thereby enhancing their quality of life.
  • Studies suggest cannabis influences brain cells that regulate hunger, potentially aiding appetite issues in cancer patients and others.
  • THC capsules are precise, convenient, discreet, and long-lasting, making them perfect for medical marijuana users who prefer not to smoke.

Cancer Cachexia and Anorexia Syndrome

Cachexia is a condition characterized by significant weight loss caused by the depletion of muscle and fat, typically seen in patients with advanced diseases such as heart failure, HIV/AIDS, COPD, kidney failure, and particularly cancer.

This condition usually coincides with anorexia, which signifies a decreased appetite leading to at least a 5% reduction in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS).

Hospitalized cancer patients often exhibit poor dietary intake, with nearly half being malnourished or at risk. Cachexia not only diminishes the quality of life for patients but also obstructs treatment and may hasten the end of life. Its prevalence escalates sharply as death approaches, with cachexia identified as the primary cause of death in over 20% of cases.

Despite its common occurrence, CACS frequently goes unnoticed and untreated in clinical environments due to the absence of clear definitions, diagnostic criteria, classification systems, and approved therapies. Clinicians evaluate a patient’s nutritional status using various measures such as body weight, skin fold thickness, and mid-arm circumference, though body weight is often the primary focus, typically relying on inappropriate reference weights.

Treatment

The most apparent method to address anorexia is to enhance nutrition – yet evidence supporting its effectiveness remains limited. For cancer patients, nutritional care includes:

  • Dietary Counseling
  • Oral Supplements
  • Enteral and Parenteral Nutrition

However, success varies depending on the type and stage of cancer.

Pharmacological Approaches

Currently, no verified medications exist for treating Cancer Anorexia-Cachexia Syndrome (CACS), though some drugs are used off-label or are undergoing clinical trials. These medications can be categorized into four groups based on their mechanisms:

  • Appetite Stimulants
  • Cytokine Modulators
  • Anabolic Agents
  • Combination Therapies

Additionally, megestrol acetate, a progestin, is utilized separately due to its unclear mechanism of action.

Cannabis in Medicine

The cannabinoid could enhance the lives of cancer patients and pave the way for future treatments. This offers hope for cachexia patients, a condition characterized by a loss of appetite and malnourishment. It provides relief without intoxicating effects, making it a promising solution for these patients.

Diverse cannabis formulations with varying effects are available, including inhaled THC for quick onset and brief effects and orally ingested THC for slower absorption and prolonged effects. Sublingual administration provides rapid onset and lasts for 2 to 4 hours.

Clinical Trial

A study conducted by researchers from Israel and the United States evaluated how cannabis pills affect CACS in advanced cancer patients. This discovery significantly impacts the treatment of appetite disorders faced by cancer patients, individuals with anorexia, and potentially those with obesity.

Methods

They utilized cannabis capsules containing two types of oil-based compounds, planning to treat participants with 10 mg doses twice daily for six months, which included 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).

If participants experienced side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). At each doctor’s visit, participants were weighed, with the main goal being a gain of at least 10% more weight than their starting weight.

Results

Out of 24 patients who consented to participate, 17 commenced treatment with cannabis capsules. However, only 11 continued taking the capsules for over two weeks. At the study’s conclusion, 3 out of 6 patients who completed the treatment achieved the primary goal of gaining at least 10% more weight. The weight of the remaining three patients remained unchanged.

Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Patients reported improved appetite and mood, with reduced pain and fatigue.

Despite several challenges, this preliminary study demonstrated a weight gain of 10% or more in 3 out of 17 patients (17.6%) taking daily doses of 5 mg once or twice without notable side effects. These findings advocate for conducting a larger, more controlled study on cannabis capsules in patients with CACS.

Cannabis Capsules

If you enjoy edibles, cannabis flower, or classic pre-rolls, discovering new ways to enjoy cannabis is always thrilling.

THC capsules from CannaBlossom Canada represent one of the latest additions to the cannabis market. These capsules are cannabis pills containing a precise dose of THC, derived from concentrated cannabis extract and a neutral oil. They are akin to cannabis tinctures in capsule form (also known as cannabis oil capsules or THC pills).

Key Components

  • Cannabis Extract: This concentrated extract is obtained from the cannabis plant using a method selected by the manufacturer for extraction. THC capsules are rich in THC, though some may contain only CBD or varying CBD/THC ratios.
  • Neutral Oil Suspension: THC is not soluble in water, so it is suspended in an oil for proper absorption by the body. The most common oils used are CannaBlossom Canada, aiding digestion and absorption.

Benefits

Medical marijuana patients and recreational users can benefit from cannabis capsules. They provide:

  • Convenience: Taking a cannabis capsule is as straightforward as any other oral supplement. Just swallow it with water, no fuss.
  • Precision Dosage: For medical users, precise control over cannabinoid intake is vital for achieving desired effects. With THC capsules, each dose is measured, eliminating guesswork.
  • Smoke-Free Option: Many individuals prefer to avoid smoking or vaping due to personal choices or health concerns. THC capsules offer a smoke-free alternative, suitable for those with respiratory issues.
  • Longer Effects: Capsules typically provide longer-lasting effects compared to smoking or vaping, rendering them ideal for sustained symptom relief over several hours.

Cannabis Capsules vs. Other Forms of Medicinal Cannabis

AspectCannabis CapsulesOther Forms of Medicinal Cannabis
DosingPrecise dosing with each capsuleDosing may vary depending on the method of consumption (e.g., smoking, vaping, edibles)
ConsumptionOral ingestionSmoking, vaping, edibles, tinctures
EffectsLonger-lasting, gradual onsetImmediate onset, shorter duration
Effects on Appetite StimulationGradual stimulationImmediate stimulation

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If you’re seeking cannabis flower, pre-rolls, edibles, or vape pens, you can effortlessly browse through CannaBlossom Canada’s finest marijuana products sourced from premium marijuana plants. Shop for your favorite THC products from the comfort of your own home.

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Frequently Asked Questions

What are the different types of capsules?

One more advantage of cannabis pills/capsules is their versatility – formulators can create various capsule types for consumers to select from. This means you can find capsules tailored to your personal preference.

  1. 1:1 Capsules: These capsules deliver an equal ratio of THC to CBD in each dose. They can be produced with sativa or indica strains and come in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
  2. 3:1 Capsules: These capsules deliver a ratio of 3 parts CBD to 1 part THC in each dose.
  3. THC Capsules: These capsules contain THC only, with varying concentrations per capsule, derived from different Sativa or Indica strains to offer specific effects.
  4. CBD Capsules: These only contain CBD, without THC, so they don’t produce mind-altering effects. They’re designed for individuals seeking the benefits of CBD alone.

How do capsules interact with your body?

  1. The capsule’s outer shell disintegrates in your digestive tract once you consume it.
  2. The capsule’s contents are absorbed into the bloodstream.
  3. THC (and other cannabinoids) are metabolized in the liver.

How long does it take for cannabis capsule effects to kick in?

Typically, THC capsules take about 90 minutes to begin showing effects. The effects can last from 5 to 12 hours, gradually diminishing in intensity. Compared to inhaled cannabis, capsule effects tend to last twice as long on average.

However, experiences may vary based on factors like age, medications, personal cannabis tolerance, and cannabinoid composition. Some users also observe different effects based on specific cannabinoids present, potentially due to the “entourage effect.”

How to mail order marijuana?

To mail order recreational cannabis, find a trustworthy delivery service online that offers the best quality cannabis products. After selecting your items, choose “order cannabis delivery,” and a delivery driver will safely bring your order. Ensure the service is reputable for a smooth purchasing experience.

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